CMPK1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CMPK1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CMPK1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CMPK1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CMPK1 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and UCEC are the cancer types where CMPK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianAll1.0000.887.02248view →
PDACOSQuartileII,III,IV0.6380.320.00843view →
UCECDFSTertileAll1.0000.787.00228view →
GBMOSMedianAll0.2790.468.00525view →
LUADDFSQuartileII,III,IV0.6750.214.0186view →
CCRCCDFSQuartileII,III,IV0.9330.728.0295view →
LSCCOSMedianAll0.6990.883.0162view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CMPK1–COAD (DFS)

Kaplan–Meier survival curve for CMPK1 mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration