CMPK1

Across TCGA patient cohorts, CMPK1 mutation is significantly associated with the RNA expression of many other genes, with 2,024 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMPK1-associated genes across cancer lineages are HSPE1-MOB4, LINC01050, and LINC01607. Each is linked with CMPK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMPK1-to-partner and partner-to-CMPK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSPE1-MOB4 grouped by CMPK1-low versus CMPK1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMPK1→partner) and Y-score (partner→CMPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSPE1-MOB4 →	+0.228	+2.329	<.001	<.001	3	1
UCEC	LINC01050 →	+0.152	+2.636	.009	<.001	3	1
UCEC	LINC01607 →	-0.919	-3.785	<.001	<.001	3	1
UCEC	CWC25 →	+0.452	+2.447	.001	.001	3	1
UCEC	ZNHIT3 →	+0.538	+3.108	<.001	<.001	3	1
UCEC	MIR6870 →	+0.312	+2.273	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,024 associations by consensus.

HSPE1-MOB4 by CMPK1 expression — UCEC

Explore this box plot interactively →