CMPK1

Across TCGA patient cohorts, CMPK1 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMPK1-associated genes across cancer lineages are eIF4E, A-Raf_pS299, and FASN. Each is linked with CMPK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMPK1-to-partner and partner-to-CMPK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by CMPK1-low versus CMPK1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMPK1→partner) and Y-score (partner→CMPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.181	+2.115	.049	.019	3	1
UCEC	A-Raf_pS299 →	-0.155	-3.584	.002	.002	3	1
UCEC	FASN →	+0.355	+3.000	.039	.036	3	1
UCEC	MEK1 →	+0.503	+2.115	.001	.019	3	1
UCEC	Myosin-IIa_pS1943 →	+0.265	+1.598	.003	.044	3	1
UCEC	Myosin-IIa →	+0.316	+1.881	<.001	.031	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

eIF4E by CMPK1 expression — UCEC

Explore this box plot interactively →