CMC2

Across TCGA patient cohorts, CMC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,512 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CMC2-associated proteins across cancer lineages are USP10, TERF2_S365, and PDS5A_T1208. Each is linked with CMC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CMC2-to-partner and partner-to-CMC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CMC2 versus USP10 in OV, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CMC2→partner) and Y-score (partner→CMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	USP10 →	+0.315	+0.430	<.001	<.001	3	7
PDAC	TERF2_S365 →	+0.654	+0.401	<.001	<.001	3	6
OV	PDS5A_T1208 →	+1.090	+0.458	.001	.001	3	6
LSCC	SPAST →	+0.364	+0.334	.003	<.001	3	5
BRCA	MVD →	+0.472	+0.372	<.001	<.001	3	5
GBM	MCM4_T110 →	+1.063	+0.324	.004	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,512 associations by consensus.

CMC2 vs USP10 — OV

Explore this scatter interactively →