Across TCGA patient cohorts, CMC1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,541 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CMC1-associated genes across cancer lineages are GPD1L, OXSM, and OXNAD1. Each is linked with CMC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CMC1-to-partner and partner-to-CMC1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMC1→partner) and Y-score (partner→CMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPD1L →	+0.679	+0.819	.001	<.001	3	4
OV	OXSM →	+0.517	+0.624	<.001	.001	3	3
OV	OXNAD1 →	+0.374	+0.566	.001	.005	3	3
OV	CHCHD4 →	+0.600	+0.878	<.001	<.001	3	3
OV	TEX264 →	+0.400	+0.584	.004	.003	2	4
OV	CHST15 →	-0.985	-0.930	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,541 associations by consensus.

Exploration

CMC1 survival (RNA) · tumor vs normal (RNA) · all CMC1 data types