Across TCGA cell cohorts, CMC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,163 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CMC1-associated GO terms across cancer lineages are Mitochondrial disulfide relay system, Purine deoxyribonucleoside monophosphate biosynthetic process, and Protein import into mitochondrial intermembrane space. Each is linked with CMC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both CMC1-to-partner and partner-to-CMC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CMC1→partner) and Y-score (partner→CMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitochondrial disulfide relay system →	+0.146	+1.184	<.001	<.001	3	11
URINARY_TRACT	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.148	+0.839	<.001	.001	3	10
KIDNEY	Protein import into mitochondrial intermembrane space →	+0.119	+1.042	.001	<.001	3	10
URINARY_TRACT	DAMP biosynthetic process →	+0.148	+0.839	<.001	.001	3	10
LUNG_NSCLC_LUAD	Cerebral cortex radial glia-guided migration →	-0.113	-0.645	.003	<.001	3	10
LUNG_NSCLC_LUAD	Telencephalon glial cell migration →	-0.113	-0.645	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,163 associations by consensus.

Exploration

CMC1 survival (RNA) · tumor vs normal (RNA) · all CMC1 data types