CMBL

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CMBL mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible CMBL-associated genes across cancer lineages are Preadipocytes and Basophils. Each is linked with CMBL in more than 1 cancer types. Because this analysis shows association rather than direction, both CMBL-to-partner and partner-to-CMBL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by CMBL-low versus CMBL-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMBL→partner) and Y-score (partner→CMBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCPreadipocytes →+0.119+5.706<.001.00332
UCECBasophils →+0.208+3.169.025.02021
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Preadipocytes by CMBL expression — LUSC

Box plot of Preadipocytes in CMBL-low vs CMBL-high samples in LUSC.

Explore this box plot interactively →

Exploration