CMAS

Across TCGA patient cohorts, CMAS RNA expression is significantly associated with the protein abundance of many other proteins, with 12,796 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CMAS-associated proteins across cancer lineages are NAA25, NOP2, and EMG1. Each is linked with CMAS in more than 5 cancer types. Because this analysis shows association rather than direction, both CMAS-to-partner and partner-to-CMAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CMAS versus NAA25 in BRCA, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CMAS→partner) and Y-score (partner→CMAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NAA25 →	+0.276	+0.424	<.001	.005	3	6
BRCA	NOP2 →	+0.604	+0.581	<.001	<.001	3	6
HNSC	EMG1 →	+0.431	+1.100	<.001	<.001	3	6
HNSC	PSME3 →	+0.285	+0.540	<.001	<.001	3	6
LSCC	NOL11 →	+0.300	+0.678	.001	<.001	3	5
BRCA	NOP2_S67 →	+0.900	+0.483	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,796 associations by consensus.

CMAS vs NAA25 — BRCA

Explore this scatter interactively →