CMAS

Across TCGA patient cohorts, CMAS protein abundance is significantly associated with the RNA expression of many other genes, with 12,561 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CMAS-associated genes across cancer lineages are DCP1B, ING4, and ETFRF1. Each is linked with CMAS in more than 6 cancer types. Because this analysis shows association rather than direction, both CMAS-to-partner and partner-to-CMAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CMAS versus DCP1B in LSCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMAS→partner) and Y-score (partner→CMAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DCP1B →	+0.611	+0.319	<.001	<.001	3	7
OV	ING4 →	+0.616	+0.484	<.001	<.001	3	7
LSCC	ETFRF1 →	+0.975	+0.343	<.001	<.001	3	7
HNSC	GBP5 →	-1.711	-0.309	<.001	.001	3	6
CCRCC	LPCAT3 →	+0.779	+0.236	<.001	.004	3	6
OV	C2CD5 →	+0.490	+0.461	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,561 associations by consensus.

CMAS vs DCP1B — LSCC

Explore this scatter interactively →