CMAS

Across TCGA cell cohorts, CMAS RNA expression is significantly associated with the go_rna of many other GO terms, with 2,855 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CMAS-associated GO terms across cancer lineages are CMP-N-acetylneuraminate metabolic process, CMP-N-acetylneuraminate biosynthetic process, and Pentose-phosphate shunt. Each is linked with CMAS in more than 10 cancer types. Because this analysis shows association rather than direction, both CMAS-to-partner and partner-to-CMAS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP-N-acetylneuraminate metabolic process grouped by CMAS-low versus CMAS-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CMAS→partner) and Y-score (partner→CMAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CMP-N-acetylneuraminate metabolic process →	+0.146	+0.880	<.001	<.001	3	11
BREAST	CMP-N-acetylneuraminate biosynthetic process →	+0.146	+0.880	<.001	<.001	3	11
BREAST	Pentose-phosphate shunt →	+0.110	+0.746	.001	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of intestinal cholesterol absorption →	+0.225	+0.478	<.001	<.001	3	8
BLOOD_Myeloma	Mitotic nuclear division →	+0.064	+0.654	.009	.002	3	7
LUNG_SCLC	Membrane fission →	+0.054	+0.604	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,855 associations by consensus.

CMP-N-acetylneuraminate metabolic process by CMAS expression — BREAST

Explore this box plot interactively →