CLUL1

Across TCGA cell cohorts, CLUL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,154 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CLUL1-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Positive regulation of monoatomic ion transport, and Golgi vesicle transport. Each is linked with CLUL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CLUL1-to-partner and partner-to-CLUL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by CLUL1-low versus CLUL1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLUL1→partner) and Y-score (partner→CLUL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of double-strand break repair →	+0.060	+1.875	<.001	.004	3	10
BONE	Positive regulation of monoatomic ion transport →	-0.151	-2.661	<.001	<.001	3	9
SKIN	Golgi vesicle transport →	+0.044	+1.169	<.001	.001	2	10
OVARY	Regulation of potassium ion transmembrane transport →	-0.140	-0.739	<.001	<.001	3	8
BONE	Peptidyl-lysine acetylation →	+0.127	+2.857	<.001	<.001	3	8
OVARY	Proton motive force-driven mitochondrial ATP synthesis →	+0.068	+0.660	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,154 associations by consensus.

Positive regulation of double-strand break repair by CLUL1 expression — BONE

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