CLUHP5

Across TCGA pan-cancer cohorts, CLUHP5 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CLUHP5 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CLUHP5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CLUHP5 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

ACC, LUSC, and CHOL are the cancer types where CLUHP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.142	0.640	<.001	90	view →
LUSC	DFS	Tertile	III,IV	0.010	0.754	<.001	78	view →
CHOL	OS	Tertile	All	0.019	0.800	<.001	54	view →
OV	OS	Tertile	II,III,IV	0.513	0.696	.011	48	view →
THCA	OS	Tertile	All	0.890	0.991	<.001	45	view →
LUAD	OS	Tertile	III,IV	0.406	0.668	.008	42	view →
PCPG	OS	Tertile	All	0.433	0.854	<.001	36	view →
READ	OS	Tertile	II,III,IV	0.542	0.918	.005	30	view →
SKCM	DFS	Tertile	III,IV	0.015	0.648	<.001	27	view →
HNSC	DFS	Tertile	III,IV	0.729	0.318	.025	21	view →
MESO	DFS	Tertile	IV	0.130	0.405	.019	18	view →
UCS	OS	Tertile	All	0.153	0.687	.019	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CLUHP5–ACC (OS)

Open the ACC breakdown →