CLUHP3

Across TCGA pan-cancer cohorts, CLUHP3 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated CLUHP3 data layer compared with 2 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher CLUHP3 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CLUHP3 expression acts as an unfavorable survival marker, although some lineages such as MESO and PAAD show a favorable association.

MESO, PAAD, and UVM are the cancer types where CLUHP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.493	0.277	<.001	83	view →
PAAD	OS	Quartile	All	0.515	0.210	<.001	71	view →
UVM	DFS	Tertile	All	0.718	0.366	.003	62	view →
COAD	OS	Tertile	All	0.670	0.880	<.001	44	view →
READ	OS	Median	All	0.965	0.312	.001	37	view →
BRCA	OS	Median	III,IV	0.963	0.840	<.001	34	view →
SKCM	OS	Median	IV	0.867	0.225	.001	33	view →
UCEC	DFS	Median	All	0.790	0.879	.001	32	view →
HNSC	OS	Median	All	0.716	0.604	.002	30	view →
KIRC	OS	Tertile	All	0.714	0.563	.003	29	view →
LUAD	OS	Median	II,III,IV	0.650	0.481	.005	25	view →
PRAD	DFS	Median	All	0.837	0.925	.001	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

CLUHP3–MESO (OS)

Open the MESO breakdown →