Across TCGA pan-cancer cohorts, CLUHP3 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CLUHP3 data layer compared with 21 for mass-spec protein.
The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CLUHP3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CLUHP3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.
CCRCC and GBM are the cancer types where CLUHP3 mass-spec protein most reproducibly stratifies survival.