CLUHP1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLUHP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,556 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CLUHP1-associated GO terms across cancer lineages are Regulation of cartilage development, Regulation of protein tyrosine kinase activity, and Positive regulation of biomineral tissue development. Each is linked with CLUHP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLUHP1-to-partner and partner-to-CLUHP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cartilage development grouped by CLUHP1-low versus CLUHP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLUHP1→partner) and Y-score (partner→CLUHP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCARegulation of cartilage development →+0.052+0.006.003.00132
ESCARegulation of protein tyrosine kinase activity →+0.062+0.009.002.00132
ESCAPositive regulation of biomineral tissue development →+0.053+0.007.001.00432
ESCANucleotide-binding oligomerization domain containing 2 signaling pathway →+0.075+0.006.004.00132
ESCAPlatelet aggregation →+0.055+0.012.003.00132
ESCATransforming growth factor beta production →+0.069+0.006.009.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,556 associations by consensus.

Regulation of cartilage development by CLUHP1 expression — ESCA

Box plot of Regulation of cartilage development in CLUHP1-low vs CLUHP1-high samples in ESCA.

Explore this box plot interactively →

Exploration