CLU

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLU RNA expression is significantly associated with the protein abundance of many other proteins, with 20,840 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CLU-associated proteins across cancer lineages are PHYHD1, RPS2, and ANK2_S890. Each is linked with CLU in more than 5 cancer types. Because this analysis shows association rather than direction, both CLU-to-partner and partner-to-CLU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLU versus PHYHD1 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLU→partner) and Y-score (partner→CLU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPHYHD1 →+0.558+1.271<.001.00336
PDACRPS2 →-0.222-0.808.003.00736
LSCCANK2_S890 →+1.114+1.338<.001<.00136
LSCCUTP4 →-0.321-0.839<.001.00236
LSCCRCL1 →-0.284-0.675<.001<.00136
GBMEPHX2 →+0.634+0.844<.001.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,840 associations by consensus.

CLU vs PHYHD1 — COAD

Per-sample scatter of CLU vs PHYHD1 in COAD (Pearson r = 0.39).

Explore this scatter interactively →

Exploration