CLTCL1

Across TCGA patient cohorts, CLTCL1 protein abundance is significantly associated with the RNA expression of many other genes, with 888 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CLTCL1-associated genes across cancer lineages are SLC3A1, RPL13P2, and RPL5P24. Each is linked with CLTCL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLTCL1-to-partner and partner-to-CLTCL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLTCL1 versus SLC3A1 in LSCC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTCL1→partner) and Y-score (partner→CLTCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC3A1 →	-0.224	-0.412	.002	.003	3	2
CCRCC	RPL13P2 →	-0.266	-0.487	<.001	<.001	3	2
CCRCC	RPL5P24 →	-0.780	-0.501	.001	.002	3	2
GBM	ASMTL →	+0.836	+0.559	.003	.007	3	1
COAD	SLCO4A1 →	-1.755	-0.545	.001	.007	3	1
COAD	CTCF →	-1.040	-0.545	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 888 associations by consensus.

CLTCL1 vs SLC3A1 — LSCC

Explore this scatter interactively →