CLTB

Across TCGA patient cohorts, CLTB protein abundance is significantly associated with the RNA expression of many other genes, with 16,652 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CLTB-associated genes across cancer lineages are FANCG, MMP28, and E2F1. Each is linked with CLTB in more than 6 cancer types. Because this analysis shows association rather than direction, both CLTB-to-partner and partner-to-CLTB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLTB versus FANCG in HNSC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTB→partner) and Y-score (partner→CLTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FANCG →	-0.521	-0.371	<.001	<.001	3	7
HNSC	MMP28 →	+1.556	+0.399	<.001	<.001	3	7
BRCA	E2F1 →	-1.114	-0.326	<.001	<.001	3	6
UCEC	E2F3 →	-0.624	-0.419	<.001	<.001	3	6
BRCA	NCAPH →	-0.841	-0.339	<.001	<.001	3	6
BRCA	LYAR →	-0.527	-0.264	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,652 associations by consensus.

CLTB vs FANCG — HNSC

Explore this scatter interactively →