CLTB

Across TCGA cell cohorts, CLTB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,657 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CLTB-associated GO terms across cancer lineages are Clathrin coat disassembly, Regulation of type B pancreatic cell development, and Protein targeting to membrane. Each is linked with CLTB in more than 14 cancer types. Because this analysis shows association rather than direction, both CLTB-to-partner and partner-to-CLTB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Clathrin coat disassembly grouped by CLTB-low versus CLTB-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTB→partner) and Y-score (partner→CLTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Clathrin coat disassembly →	+0.158	+1.147	<.001	.009	2	15
LUNG_NSCLC_LUSC	Regulation of type B pancreatic cell development →	+0.131	+1.081	.005	.009	1	12
BONE	Protein targeting to membrane →	+0.083	+1.329	.001	.001	3	10
SKIN	Latent virus replication →	+0.186	+0.956	<.001	<.001	3	10
SKIN	Release from viral latency →	+0.186	+0.956	<.001	<.001	3	10
PANCREAS	Positive regulation of type B pancreatic cell development →	+0.216	+0.816	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,657 associations by consensus.

Clathrin coat disassembly by CLTB expression — BLOOD_Myeloma

Explore this box plot interactively →