CLTA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLTA RNA expression is significantly associated with the protein abundance of many other proteins, with 9,148 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLTA-associated proteins across cancer lineages are UBAP2, DNAJA1, and PRRC2B. Each is linked with CLTA in more than 6 cancer types. Because this analysis shows association rather than direction, both CLTA-to-partner and partner-to-CLTA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLTA versus UBAP2 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTA→partner) and Y-score (partner→CLTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCUBAP2 →+0.487+0.635<.001<.00137
LSCCDNAJA1 →+0.292+0.621<.001<.00137
COADPRRC2B →+0.295+0.487.003<.00135
LSCCSTOML2 →+0.561+0.812<.001<.00135
OVUBE2R2 →+0.394+0.408.004.00934
LSCCNFX1 →+0.302+0.728<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,148 associations by consensus.

CLTA vs UBAP2 — LSCC

Per-sample scatter of CLTA vs UBAP2 in LSCC (Pearson r = 0.55).

Explore this scatter interactively →

Exploration