CLTA

Across TCGA patient cohorts, CLTA protein abundance is significantly associated with the RNA expression of many other genes, with 8,787 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CLTA-associated genes across cancer lineages are STOML2, CREB3, and GRHPR. Each is linked with CLTA in more than 5 cancer types. Because this analysis shows association rather than direction, both CLTA-to-partner and partner-to-CLTA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLTA versus STOML2 in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTA→partner) and Y-score (partner→CLTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STOML2 →	+0.971	+0.207	<.001	<.001	3	6
UCEC	CREB3 →	+1.071	+0.186	<.001	.001	3	5
UCEC	GRHPR →	+0.580	+0.154	<.001	.001	3	4
HNSC	UBE2R2 →	+0.548	+0.270	.002	<.001	3	4
UCEC	LRRC59 →	+0.645	+0.191	<.001	<.001	3	3
CCRCC	LTBP1 →	-1.042	-0.176	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,787 associations by consensus.

CLTA vs STOML2 — UCEC

Explore this scatter interactively →