CLTA

Across TCGA patient cohorts, CLTA mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible CLTA-associated genes across cancer lineages are Monocytes. Each is linked with CLTA in more than 1 cancer types. Because this analysis shows association rather than direction, both CLTA-to-partner and partner-to-CLTA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by CLTA-low versus CLTA-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTA→partner) and Y-score (partner→CLTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Monocytes →	+0.020	+5.797	<.001	.035	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Monocytes by CLTA expression — KIRP

Explore this box plot interactively →