CLTA

Across TCGA cell cohorts, CLTA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,457 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLTA-associated GO terms across cancer lineages are Latent virus replication, Release from viral latency, and Clathrin coat disassembly. Each is linked with CLTA in more than 11 cancer types. Because this analysis shows association rather than direction, both CLTA-to-partner and partner-to-CLTA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Latent virus replication grouped by CLTA-low versus CLTA-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTA→partner) and Y-score (partner→CLTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Latent virus replication →	+0.203	+0.908	.004	<.001	3	12
LUNG_NSCLC_LUSC	Release from viral latency →	+0.203	+0.908	.004	<.001	3	12
STOMACH	Clathrin coat disassembly →	+0.106	+0.628	.001	<.001	3	11
SOFT_TISSUE	Protein monoubiquitination →	+0.051	+0.891	.001	<.001	3	8
OESOPHAGUS	Nuclear-transcribed mRNA catabolic process, no-go decay →	+0.105	+0.697	<.001	<.001	3	8
CNS	Endocytic recycling →	+0.087	+0.590	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,457 associations by consensus.

Latent virus replication by CLTA expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →