CLSTN3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CLSTN3 mutation is significantly associated with the RNA expression of many other genes, with 535 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLSTN3-associated genes across cancer lineages are FABP9, KIF2B, and OR1M1. Each is linked with CLSTN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLSTN3-to-partner and partner-to-CLSTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FABP9 grouped by CLSTN3-low versus CLSTN3-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLSTN3→partner) and Y-score (partner→CLSTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTFABP9 →+0.042+4.087<.001.00931
BLOOD_LymphomaKIF2B →+0.006+5.209<.001.00531
BLOOD_LymphomaOR1M1 →+0.019+5.209<.001.00531
BLOOD_LymphomaKRTAP4-4 →+0.022+5.643<.001.00231
BLOOD_LymphomaOR10K1 →+0.012+4.867<.001.00931
BLOOD_LymphomaOR9A2 →+0.029+5.209<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 535 associations by consensus.

FABP9 by CLSTN3 expression — URINARY_TRACT

Box plot of FABP9 in CLSTN3-low vs CLSTN3-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration