CLSTN2

Across TCGA patient cohorts, CLSTN2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,950 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CLSTN2-associated genes across cancer lineages are BAG1, PER2, and INTS12. Each is linked with CLSTN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLSTN2-to-partner and partner-to-CLSTN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLSTN2 versus BAG1 in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLSTN2→partner) and Y-score (partner→CLSTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BAG1 →	+0.663	+0.917	<.001	<.001	3	2
BRCA	PER2 →	+0.681	+0.755	<.001	<.001	3	2
BRCA	INTS12 →	+0.392	+0.922	<.001	<.001	3	2
BRCA	STEAP2 →	+1.309	+0.777	<.001	<.001	3	2
PDAC	FBXO8 →	+0.344	+0.692	.003	.003	3	2
GBM	CACNG2 →	+0.507	+0.502	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,950 associations by consensus.

CLSTN2 vs BAG1 — BRCA

Explore this scatter interactively →