CLSTN2

Across TCGA cell cohorts, CLSTN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,583 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CLSTN2-associated GO terms across cancer lineages are Protein-DNA complex organization, Presynaptic active zone organization, and Protein-DNA complex assembly. Each is linked with CLSTN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CLSTN2-to-partner and partner-to-CLSTN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by CLSTN2-low versus CLSTN2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLSTN2→partner) and Y-score (partner→CLSTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein-DNA complex organization →	+0.070	+2.268	<.001	<.001	3	8
SOFT_TISSUE	Presynaptic active zone organization →	-0.135	-1.073	.002	.001	3	7
LUNG_SCLC	Protein-DNA complex assembly →	+0.069	+2.165	<.001	.003	3	7
SKIN	ATP synthesis coupled electron transport →	+0.061	+0.456	.002	.004	2	8
SKIN	Mitochondrial ATP synthesis coupled electron transport →	+0.061	+0.456	.002	.004	2	8
UPPER_AERODIGESTIVE_TRACT	Response to L-glutamate →	+0.172	+0.290	.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,583 associations by consensus.

Protein-DNA complex organization by CLSTN2 expression — BONE

Explore this box plot interactively →