CLRN3

Across TCGA cell cohorts, CLRN3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CLRN3-associated genes across cancer lineages are MAGEB4 and NEUROD4. Each is linked with CLRN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLRN3-to-partner and partner-to-CLRN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by CLRN3-low versus CLRN3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLRN3→partner) and Y-score (partner→CLRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MAGEB4 →	+0.005	+3.700	<.001	.005	3	1
OVARY	NEUROD4 →	+0.009	+3.700	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MAGEB4 by CLRN3 expression — OVARY

Explore this box plot interactively →