CLPX

Across TCGA cell cohorts, CLPX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,504 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLPX-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Metaphase/anaphase transition of mitotic cell cycle, and Metaphase/anaphase transition of cell cycle. Each is linked with CLPX in more than 14 cancer types. Because this analysis shows association rather than direction, both CLPX-to-partner and partner-to-CLPX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by CLPX-low versus CLPX-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLPX→partner) and Y-score (partner→CLPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Establishment of protein localization to organelle →	+0.060	+1.198	<.001	<.001	3	15
OESOPHAGUS	Metaphase/anaphase transition of mitotic cell cycle →	+0.155	+0.665	.003	.007	3	15
OESOPHAGUS	Metaphase/anaphase transition of cell cycle →	+0.159	+0.659	.002	.008	3	15
BONE	Transcription elongation by RNA polymerase II →	+0.104	+0.796	<.001	<.001	3	15
BONE	Regulation of transcription initiation by RNA polymerase II →	+0.076	+0.661	.003	.006	3	14
BONE	Nucleic acid transport →	+0.098	+0.596	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,504 associations by consensus.

Establishment of protein localization to organelle by CLPX expression — BLOOD_Lymphoma

Explore this box plot interactively →