Across TCGA patient cohorts, CLPSL1 mutation is significantly associated with the RNA expression of many other genes, with 100 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLPSL1-associated genes across cancer lineages are AQP7P2, MIR380, and RNU6-222P. Each is linked with CLPSL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLPSL1-to-partner and partner-to-CLPSL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLPSL1→partner) and Y-score (partner→CLPSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AQP7P2 →	+0.338	+3.595	<.001	.001	3	1
UCEC	MIR380 →	+0.333	+4.464	<.001	.005	3	1
UCEC	RNU6-222P →	+0.595	+3.224	<.001	.004	3	1
UCEC	RNU1-17P →	+0.246	+3.198	.005	.009	3	1
UCEC	RNU6-1155P →	+0.221	+5.475	<.001	.001	3	1
UCEC	RNU6-1085P →	+0.542	+3.599	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 100 associations by consensus.

Exploration

CLPSL1 survival (RNA) · tumor vs normal (RNA) · all CLPSL1 data types