CLPS

Across TCGA patient cohorts, CLPS RNA expression is significantly associated with the protein abundance of many other proteins, with 9,321 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CLPS-associated proteins across cancer lineages are POU2F1, PRRC2A, and SRCIN1. Each is linked with CLPS in more than 2 cancer types. Because this analysis shows association rather than direction, both CLPS-to-partner and partner-to-CLPS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLPS versus POU2F1 in UCEC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLPS→partner) and Y-score (partner→CLPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POU2F1 →	+0.250	+1.112	<.001	<.001	3	3
PDAC	PRRC2A →	+0.199	+4.081	<.001	<.001	3	3
PDAC	SRCIN1 →	+0.537	+4.500	<.001	<.001	3	3
PDAC	CNOT11 →	+0.159	+3.115	<.001	<.001	3	3
LSCC	SF3B2 →	+0.141	+0.659	.009	.003	3	3
PDAC	SLC37A4 →	+0.431	+4.019	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,321 associations by consensus.

CLPS vs POU2F1 — UCEC

Explore this scatter interactively →