CLP1

Across TCGA pan-cancer cohorts, CLP1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CLP1 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CLP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CLP1 expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

COAD, LIHC, and TGCT are the cancer types where CLP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.056	0.871	<.001	18	view →
LIHC	DFS	Median	All	0.120	0.544	.011	12	view →
TGCT	DFS	Median	All	0.146	0.801	.020	6	view →
SKCM	OS	Median	II,III,IV	0.245	0.731	.014	6	view →
STAD	DFS	Median	III,IV	0.827	0.320	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CLP1–COAD (OS)

Open the COAD breakdown →