CLP1

Across TCGA pan-cancer cohorts, CLP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CLP1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CLP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

CCRCC, HNSC, and LSCC are the cancer types where CLP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.762	0.958	.011	11	view →
HNSC	DFS	Median	IV	0.686	0.871	.030	7	view →
LSCC	DFS	Median	II,III,IV	0.856	0.533	.008	7	view →
GBM	OS	Quartile	All	0.548	0.321	.025	6	view →
PDAC	OS	Median	III,IV	0.557	0.318	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CLP1–CCRCC (DFS)

Open the CCRCC breakdown →