CLP1

Across TCGA patient cohorts, CLP1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,131 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLP1-associated genes across cancer lineages are TSEN2, DDIAS, and IRAG1. Each is linked with CLP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CLP1-to-partner and partner-to-CLP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLP1 versus TSEN2 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLP1→partner) and Y-score (partner→CLP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TSEN2 →	+0.558	+0.217	<.001	<.001	3	6
LSCC	DDIAS →	+0.761	+0.197	<.001	<.001	3	6
OV	IRAG1 →	-0.924	-0.247	.007	.003	3	6
BRCA	OIP5 →	+0.718	+0.290	<.001	<.001	3	5
BRCA	DCN →	-1.314	-0.210	<.001	<.001	3	5
LSCC	HROB →	+0.803	+0.225	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,131 associations by consensus.

CLP1 vs TSEN2 — LSCC

Explore this scatter interactively →