CLP1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CLP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,345 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLP1-associated GO terms across cancer lineages are Regulation of mRNA 3'-end processing, Spliceosomal snRNP assembly, and Regulation of attachment of mitotic spindle microtubules to kinetochore. Each is linked with CLP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both CLP1-to-partner and partner-to-CLP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA 3'-end processing grouped by CLP1-low versus CLP1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLP1→partner) and Y-score (partner→CLP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYRegulation of mRNA 3'-end processing →+0.128+0.623<.001<.001318
BONESpliceosomal snRNP assembly →+0.076+0.509.002<.001315
UPPER_AERODIGESTIVE_TRACTRegulation of attachment of mitotic spindle microtubules to kinetochore →+0.184+0.756<.001<.001315
SOFT_TISSUESpliceosomal tri-snRNP complex assembly →+0.100+0.724<.001<.001315
BONEtRNA-type intron splice site recognition and cleavage →+0.165+0.849<.001<.001314
UPPER_AERODIGESTIVE_TRACTPositive regulation of attachment of mitotic spindle microtubules to kinetochore →+0.195+0.730<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,345 associations by consensus.

Regulation of mRNA 3'-end processing by CLP1 expression — OVARY

Box plot of Regulation of mRNA 3'-end processing in CLP1-low vs CLP1-high samples in OVARY.

Explore this box plot interactively →

Exploration