Across TCGA pan-cancer cohorts, CLNS1AP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CLNS1AP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CLNS1AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CLNS1AP1 is over-expressed in tumor.

HNSC, COAD, and UCEC are the cancer types where CLNS1AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLNS1AP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.044	.002	6	view →
COAD	All	II,III,IV	+0.107	.007	5	view →
UCEC	All	All	+0.188	.029	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: CLNS1AP1 RNA expression & survival · all CLNS1AP1 data types