CLNS1A

Across TCGA cell cohorts, CLNS1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,966 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CLNS1A-associated GO terms across cancer lineages are Asparaginyl-tRNA aminoacylation, Negative regulation of double-strand break repair, and Negative regulation of DNA repair. Each is linked with CLNS1A in more than 16 cancer types. Because this analysis shows association rather than direction, both CLNS1A-to-partner and partner-to-CLNS1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Asparaginyl-tRNA aminoacylation grouped by CLNS1A-low versus CLNS1A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLNS1A→partner) and Y-score (partner→CLNS1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Asparaginyl-tRNA aminoacylation →	+0.175	+0.865	<.001	.001	3	17
LIVER	Negative regulation of double-strand break repair →	+0.079	+0.651	.001	.009	3	11
LIVER	Negative regulation of DNA repair →	+0.057	+0.691	.006	<.001	3	11
CNS	mRNA methylguanosine-cap decapping →	+0.057	+0.552	<.001	.002	3	10
PANCREAS	snRNA pseudouridine synthesis →	+0.078	+0.605	.005	.001	3	10
SOFT_TISSUE	snRNA processing →	+0.072	+0.754	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,966 associations by consensus.

Asparaginyl-tRNA aminoacylation by CLNS1A expression — SOFT_TISSUE

Explore this box plot interactively →