CLNK

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLNK RNA expression is significantly associated with the protein abundance of many other proteins, with 14,750 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLNK-associated proteins across cancer lineages are LCP1, SEPTIN1, and ADA2. Each is linked with CLNK in more than 9 cancer types. Because this analysis shows association rather than direction, both CLNK-to-partner and partner-to-CLNK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLNK versus LCP1 in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLNK→partner) and Y-score (partner→CLNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMLCP1 →+0.756+0.223.001<.001310
LSCCSEPTIN1 →+0.870+0.748<.001<.00139
UCECADA2 →+0.587+0.801.002<.00139
HNSCCD38 →+0.876+0.727<.001<.00139
LSCCCORO1A →+0.648+0.721<.001<.00139
LSCCDOCK2 →+0.642+0.750<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,750 associations by consensus.

CLNK vs LCP1 — GBM

Per-sample scatter of CLNK vs LCP1 in GBM (Pearson r = 0.38).

Explore this scatter interactively →

Exploration