CLNK

Across TCGA patient cohorts, CLNK protein abundance is significantly associated with the RNA expression of many other genes, with 543 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CLNK-associated genes across cancer lineages are PEX7, ADGRG6, and MARK1. Each is linked with CLNK in more than 1 cancer types. Because this analysis shows association rather than direction, both CLNK-to-partner and partner-to-CLNK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLNK versus PEX7 in LUAD, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLNK→partner) and Y-score (partner→CLNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PEX7 →	-0.492	-0.578	.009	.006	3	1
LUAD	ADGRG6 →	-1.189	-0.770	<.001	.002	3	1
LUAD	MARK1 →	-1.100	-0.672	.001	.009	3	1
LUAD	MYCL →	-0.498	-0.688	.009	.001	3	1
LUAD	UBE3D →	-0.645	-0.803	<.001	.001	3	1
LUAD	VAPB →	-0.711	-0.803	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 543 associations by consensus.

CLNK vs PEX7 — LUAD

Explore this scatter interactively →