CLN8

Across TCGA patient cohorts, CLN8 protein abundance is significantly associated with the RNA expression of many other genes, with 3,483 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLN8-associated genes across cancer lineages are E2F2, RAVER2, and CEP85. Each is linked with CLN8 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLN8-to-partner and partner-to-CLN8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLN8 versus E2F2 in UCEC, with a Pearson correlation of -0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLN8→partner) and Y-score (partner→CLN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	E2F2 →	-1.161	-0.959	.002	.008	3	4
LUAD	RAVER2 →	-1.186	-0.695	<.001	<.001	3	3
UCEC	CEP85 →	-0.918	-0.740	.004	.007	3	3
HNSC	PGD →	-1.564	-0.549	.001	.002	3	3
UCEC	H1-2 →	-2.823	-0.988	.001	.004	3	3
UCEC	TNFSF12 →	+1.168	+0.835	.004	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,483 associations by consensus.

CLN8 vs E2F2 — UCEC

Explore this scatter interactively →