CLN8

Across TCGA cell cohorts, CLN8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,359 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CLN8-associated GO terms across cancer lineages are Endosomal transport, Vacuolar transport, and Schwann cell development. Each is linked with CLN8 in more than 13 cancer types. Because this analysis shows association rather than direction, both CLN8-to-partner and partner-to-CLN8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by CLN8-low versus CLN8-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLN8→partner) and Y-score (partner→CLN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Endosomal transport →	+0.067	+0.729	<.001	<.001	3	14
STOMACH	Vacuolar transport →	+0.070	+0.643	.003	.008	3	14
URINARY_TRACT	Schwann cell development →	+0.125	+0.952	<.001	.004	2	13
BLOOD_Lymphoma	Cytosolic transport →	+0.049	+0.611	<.001	.001	3	12
KIDNEY	Endosome organization →	+0.079	+0.906	.001	<.001	3	12
BREAST	Protein targeting →	+0.057	+1.315	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,359 associations by consensus.

Endosomal transport by CLN8 expression — STOMACH

Explore this box plot interactively →