CLN5

Across TCGA patient cohorts, CLN5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,332 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CLN5-associated proteins across cancer lineages are ARHGEF7, NAXD, and FARP1. Each is linked with CLN5 in more than 7 cancer types. Because this analysis shows association rather than direction, both CLN5-to-partner and partner-to-CLN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLN5 versus ARHGEF7 in LSCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLN5→partner) and Y-score (partner→CLN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF7 →	+0.238	+0.416	<.001	<.001	3	8
COAD	NAXD →	+0.502	+0.336	<.001	<.001	3	7
OV	FARP1 →	+0.519	+0.561	<.001	<.001	3	7
OV	DOCK9 →	+0.347	+0.367	<.001	<.001	3	6
OV	GPALPP1 →	+0.469	+0.381	<.001	<.001	2	7
BRCA	TDRD3 →	+0.231	+0.406	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,332 associations by consensus.

CLN5 vs ARHGEF7 — LSCC

Explore this scatter interactively →