CLN5

Across TCGA patient cohorts, CLN5 protein abundance is significantly associated with the RNA expression of many other genes, with 8,695 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLN5-associated genes across cancer lineages are KIF11, CEP55, and SPC24. Each is linked with CLN5 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLN5-to-partner and partner-to-CLN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLN5 versus KIF11 in COAD, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLN5→partner) and Y-score (partner→CLN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KIF11 →	-0.868	-0.628	.005	.001	3	4
LUAD	CEP55 →	-1.161	-0.465	<.001	<.001	3	4
LUAD	SPC24 →	-0.885	-0.395	<.001	.001	3	4
BRCA	FNDC3A →	+0.531	+0.389	.002	.006	3	4
BRCA	ASAH1 →	+0.870	+0.566	<.001	<.001	3	4
BRCA	UBL3 →	+0.595	+0.393	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,695 associations by consensus.

CLN5 vs KIF11 — COAD

Explore this scatter interactively →