CLN5

Across TCGA cell cohorts, CLN5 RNA expression is significantly associated with the RNA expression of many other genes, with 6,902 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CLN5-associated genes across cancer lineages are FBXL3, TM9SF2, and DIS3. Each is linked with CLN5 in more than 17 cancer types. Because this analysis shows association rather than direction, both CLN5-to-partner and partner-to-CLN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLN5 versus FBXL3 in OESOPHAGUS, with a Pearson correlation of 0.74.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLN5→partner) and Y-score (partner→CLN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	FBXL3 →	+1.168	+0.994	<.001	<.001	3	18
LUNG_SCLC	TM9SF2 →	+1.463	+1.294	<.001	<.001	3	17
LUNG_SCLC	DIS3 →	+1.078	+1.080	<.001	<.001	2	16
LUNG_SCLC	DNAJC3 →	+1.499	+1.070	<.001	<.001	2	15
BLOOD_Leukemia	ALG11 →	+1.026	+0.855	<.001	<.001	3	14
LUNG_SCLC	GPR180 →	+1.116	+1.029	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,902 associations by consensus.

CLN5 vs FBXL3 — OESOPHAGUS

Explore this scatter interactively →