Across TCGA patient cohorts, CLN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,490 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CLN3-associated proteins across cancer lineages are RPL4, APOBR, and APOBR_T572. Each is linked with CLN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLN3-to-partner and partner-to-CLN3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLN3→partner) and Y-score (partner→CLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL4 →	-0.326	-0.188	<.001	.003	3	4
COAD	APOBR →	+0.358	+0.228	<.001	<.001	3	3
COAD	APOBR_T572 →	+0.465	+0.221	<.001	.001	3	3
LUAD	RPL26 →	-0.747	-0.283	<.001	<.001	3	3
LUAD	RPL3 →	-0.456	-0.209	<.001	<.001	3	3
HNSC	RPS2 →	-0.212	-0.452	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,490 associations by consensus.

Exploration

CLN3 survival (RNA) · tumor vs normal (RNA) · all CLN3 data types