CLMP

Across TCGA patient cohorts, CLMP protein abundance is significantly associated with the RNA expression of many other genes, with 5,744 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLMP-associated genes across cancer lineages are RARRES2, ST6GALNAC5, and SEMA7A. Each is linked with CLMP in more than 2 cancer types. Because this analysis shows association rather than direction, both CLMP-to-partner and partner-to-CLMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLMP versus RARRES2 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLMP→partner) and Y-score (partner→CLMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RARRES2 →	+0.965	+0.411	<.001	<.001	3	3
LUAD	ST6GALNAC5 →	+1.461	+0.887	<.001	<.001	3	3
LUAD	SEMA7A →	+0.916	+0.616	.007	<.001	3	3
COAD	RCN3 →	+1.152	+0.460	<.001	.001	3	3
LUAD	THY1 →	+1.070	+0.705	.005	.001	3	3
COAD	CHST11 →	+0.693	+0.424	.005	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,744 associations by consensus.

CLMP vs RARRES2 — LSCC

Explore this scatter interactively →