CLMP

Across TCGA patient cohorts, CLMP mutation is significantly associated with the RNA expression of many other genes, with 521 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLMP-associated genes across cancer lineages are RNU7-81P, RPL12P43, and RNA5SP437. Each is linked with CLMP in more than 2 cancer types. Because this analysis shows association rather than direction, both CLMP-to-partner and partner-to-CLMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-81P grouped by CLMP-low versus CLMP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLMP→partner) and Y-score (partner→CLMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU7-81P →	+0.436	+5.328	<.001	<.001	3	3
SKCM	RPL12P43 →	+0.087	+4.436	<.001	.001	3	2
COAD	RNA5SP437 →	+0.507	+3.289	.009	.008	3	2
CESC	OR12D2 →	+0.086	+5.418	<.001	.005	3	2
LUSC	PSMA2P1 →	+0.148	+4.019	<.001	.003	3	2
UCEC	TRAJ47 →	+0.336	+1.825	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 521 associations by consensus.

RNU7-81P by CLMP expression — SKCM

Explore this box plot interactively →