CLMP

Across TCGA cell cohorts, CLMP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,563 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CLMP-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Positive regulation of cytoskeleton organization, and Endoderm formation. Each is linked with CLMP in more than 11 cancer types. Because this analysis shows association rather than direction, both CLMP-to-partner and partner-to-CLMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by CLMP-low versus CLMP-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLMP→partner) and Y-score (partner→CLMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of focal adhesion assembly →	+0.169	+2.678	<.001	<.001	3	12
BREAST	Positive regulation of cytoskeleton organization →	+0.060	+2.480	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Endoderm formation →	+0.190	+3.139	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of smooth muscle cell-matrix adhesion →	+1.222	+2.495	.002	.001	3	11
LUNG_NSCLC_LUSC	Collagen fibril organization →	+0.289	+2.405	.002	.006	3	11
BONE	Tooth mineralization →	+0.278	+1.670	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,563 associations by consensus.

Positive regulation of focal adhesion assembly by CLMP expression — BREAST

Explore this box plot interactively →