CLMN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLMN protein abundance is significantly associated with the RNA expression of many other genes, with 12,889 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CLMN-associated genes across cancer lineages are LINC02292, TC2N, and TFF3. Each is linked with CLMN in more than 7 cancer types. Because this analysis shows association rather than direction, both CLMN-to-partner and partner-to-CLMN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLMN versus LINC02292 in CCRCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLMN→partner) and Y-score (partner→CLMN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCLINC02292 →+0.333+0.324<.001<.00138
LUADTC2N →+1.121+0.577<.001<.00136
BRCATFF3 →+3.227+0.471<.001<.00136
HNSCTMC5 →+1.540+0.432<.001<.00135
HNSCZG16B →+2.112+0.374.001<.00135
LSCCUBXN10 →+1.220+0.457<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,889 associations by consensus.

CLMN vs LINC02292 — CCRCC

Per-sample scatter of CLMN vs LINC02292 in CCRCC (Pearson r = 0.56).

Explore this scatter interactively →

Exploration