CLMN

Across TCGA cell cohorts, CLMN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,060 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CLMN-associated GO terms across cancer lineages are Flagellated sperm motility, Actin filament capping, and Barbed-end actin filament capping. Each is linked with CLMN in more than 8 cancer types. Because this analysis shows association rather than direction, both CLMN-to-partner and partner-to-CLMN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flagellated sperm motility grouped by CLMN-low versus CLMN-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLMN→partner) and Y-score (partner→CLMN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Flagellated sperm motility →	-0.088	-1.114	.006	.001	3	8
LIVER	Actin filament capping →	+0.148	+1.128	.004	.007	2	9
UPPER_AERODIGESTIVE_TRACT	Barbed-end actin filament capping →	+0.130	+1.089	.002	.008	3	8
KIDNEY	Protein targeting →	+0.054	+1.431	.001	<.001	3	8
OESOPHAGUS	Negative regulation of actin filament polymerization →	+0.151	+1.281	.001	.004	3	8
STOMACH	Regulation of actin polymerization or depolymerization →	+0.078	+1.824	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,060 associations by consensus.

Flagellated sperm motility by CLMN expression — URINARY_TRACT

Explore this box plot interactively →