CLK2P1

Across TCGA pan-cancer cohorts, CLK2P1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CLK2P1 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CLK2P1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CLK2P1 expression acts as an unfavorable survival marker.

HNSC, BLCA, and UCEC are the cancer types where CLK2P1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.156	0.710	.002	24	view →
BLCA	OS	Median	III,IV	0.188	0.654	.015	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CLK2P1–HNSC (OS)

Open the HNSC breakdown →